University seal
The Bell Lab

Lab members

Ex-members

Links

Software

Publications

Theses

Home

Recent Publications

2009 2008 2007 2006 2005 2004 2003 2002
2000 1998 1997 1996 1995 1994 1993 1992 1991

2009

  • Tracey D. Bradshaw and David R. Bell (2009) "Relevance of the aryl hydrocarbon receptor (AhR) for clinical toxicology" Clinical Toxicology 47: 632-642 pdf

  • David R. Bell (2009) "Re: Vezina et al., (2009) Biochemical Pharmacology 77:566-576" Biochemical Pharmacology 78: 104. doi:10.1016/j.bcp.2009.03.030. Corrected letter Commentary

  • Rana Bazzi, Tracey D. Bradshaw, Malcolm F. G. Stevens, J.Craig Rowlands, David R. Bell (2009) “Antitumour benzothiazoles are species-specific partial agonists of the Aryl Hydrocarbon Receptor” Toxicology and Applied Pharmacology 237: 102-110 abstract pdf

  • Tao Jiang, David R Bell, Sally Clode, Ming Qi Fan, Alwyn Fernandes, Paul M D Foster, George Loizou, Alan MacNicoll, Brian G. Miller, Martin Rose, Lang Tran, Shaun White (2009) “A truncation in the Aryl Hydrocarbon Receptor of the CRL:WI(Han) rat does not affect the developmental toxicity of TCDD” Toxicological Sciences 107: 512-521 abstract pdf article information
  • David R Bell (2009) “Environmental aneugens- the need for replication” Trends in Genetics 25: 12-13 abstract pdf
  • Ming Qi Fan, Alex R. Bell, David R Bell, Sally Clode, Alwyn Fernandes, Paul M D Foster, Jeffrey R Fry, Tao Jiang, George Loizou, Alan MacNicoll, Brian G. Miller, Martin Rose, Osama Shaikh-Omar, Lang Tran, Shaun White (2009) “Functional expression of human and rat Aryl Hydrocarbon Receptor (AhR) in Spodoptera frugiperda cells” Analytical Biochemistry 384: 279-287 abstract pdf

2008

  • Stefania Aiello, Geoffrey Wells, Erica L. Stone, Hachemi Kadri, Rana Bazzi, David R. Bell, Malcolm F. G. Stevens, Charles S. Matthews, Tracey D. Bradshaw, and Andrew D. Westwell (2008) “Synthesis and Biological Properties of Benzothiazole, Benzoxazole, and Chromen-4-one Analogues of the Potent Antitumor Agent 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648)” Journal of Medicinal Chemistry 51: 5135-5139 pdf

  • Elizabeth J. Theve, Yan Feng, Koli Taghizadeh, Kathleen S. Cormier, David R. Bell, James G. Fox, and Arlin B. Rogers (2008) “Sex hormone influence on hepatitis in young male A/JCr mice infected 1 with Helicobacter hepaticus” Infection and Immunity 76: 4071-4078 pdf
  • David R Bell, Sally Clode, Ming Qi Fan, Alwyn Fernandes, Paul M D Foster, Tao Jiang, George Loizou, Alan MacNicoll, Brian G. Miller, Martin Rose, Lang Tran, Shaun White (2008) "Report for Food Standards Agency Project T01034: Risk Assessment of Dietary Dioxins" Final Report CSL Final Report Access Database Full Acute Covance study report Part One Part Two Full Chronic Covance study report Part One Part Two
  • Abdullah Al Kholaifi, Abeer Amer, Brett Jeffery, Tim J B Gray, Ruth A Roberts, David R Bell (2008) "Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARα" Toxicological Sciences 104: 74-85 abstract pdf article information

2007

  • David R. Bell; Sally Clode; Ming Qi Fan; Alwyn Fernandes; Paul M. D. Foster; Tao Jiang; George Loizou; Alan MacNicoll; Brian G. Miller; Martin Rose; Lang Tran; Shaun White (2007) "Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) in the Developing Male Wistar(Han) Rat I: No Decrease in Epididymal Sperm Count After a Single Acute Dose " Toxicological Sciences 99: 214-223 abstract pdf Full Covance study report Part One Part Two article information
  • David R. Bell; Sally Clode; Ming Qi Fan; Alwyn Fernandes; Paul M. D. Foster; Tao Jiang; George Loizou; Alan MacNicoll; Brian G. Miller; Martin Rose; Lang Tran; Shaun White (2007) "Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) in the Developing Male Wistar(Han) Rat II: Chronic Dosing Causes Developmental Delay" Toxicological Sciences 99: 224-233 abstract pdf Full Covance study report Part One Part Two article information
  • David R. Bell; Sally Clode; Ming Qi Fan; Alwyn Fernandes; Paul M. D. Foster; Tao Jiang; George Loizou; Alan MacNicoll; Brian G. Miller; Martin Rose; Lang Tran; Shaun White (2007) "Relationships Between Tissue Levels of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), mRNAs and Toxicity in the Developing Male Wistar(Han) Rat" Toxicological Sciences 99: 591-604abstract pdf article information
  • Kristian W. Fried, Rana Bazzi, Walkiria Levy Lopez, Claudia Corsten, Karl-Werner Schramm, David R. Bell and Karl K. Rozman (2007) "Relationship between Aryl hydrocarbon receptor-affinity and the induction of EROD activity by 2,3,7,8-tetrachlorinated phenothiazine and derivatives" Toxicology and Applied Pharmacology 224: 147-159 abstract pdf

2006

  • Al-Anizy, M., Horley, N.J., Kuo, C.W.S., Gillett, L.C., Laughton, C.A., Kendall, D., Barrett, D.A., Parker, T. and Bell, D.R. (2006) "Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain" FEBS Journal 273: 936-947 article pdf

2005

  • Savas, U., Hsu, M.H., Griffin, K.J., Bell, D. R., and Johnson, E.F. (2005) "Conditional regulation of the human CYP4X1 and CYP4Z1 genes" Archives of Biochemistry and Biophysics 436: 377–385 article pdf

2004

  • Mee, C.J., Tomlinson, S.R., Perestenko, P.V., de Pomerai, D., Duce, I.R., Usherwood, P.N.R. and Bell, D.R. (2004) “Latrophilin is required for toxicity of Black Widow Spider venom in C. elegans” Biochemical Journal 378: 185-191 article pdf

  • Holmes, V.E., Bruce, M., Shaw, P.N., Bell, D.R., Fan, M.-Q., and Barrett, D.A. (2004) "A gas chromatography-mass spectrometry based method for the measurement of fatty acid w and w-1 hydroxylation kinetics by CYP4A1 using an artificial membrane system" Analytical Biochemistry 325: 354-63 article pdf

  • Choudhury, A.I., Sims, H.M., Horley, N.J., Roberts, R.A., Tomlinson, S.R., Salter, A.M., Bruce, M., Shaw, P.N., Kendall, D., Barrett, D.A., and Bell, D.R. (2004) "Molecular analysis of peroxisome proliferation in the hamster" Toxicology and Applied Pharmacology 197: 9-18 article pdf

  • Rieger, M.A., Ebner,R., Bell, D.R., Kiessling, A., Rohayem, J., Schmitz, M., Temme, A., Rieber, E.P., and Weigle, B. (2004) "Identification of a Novel Mammary-Restricted Cytochrome P450, CYP4Z1, with Overexpression in Breast Carcinoma" Cancer Research 64: 2357-2364 article pdf

  • Jeffery, B., Choudhury, A.I., Horley, N.J., Bruce, M., Tomlinson, S.R., Roberts R.A., Gray, T.J.B., Barrett, D.A., Shaw, P.N., Kendall, D., and Bell, D.R. (2004) "Peroxisome Proliferator Activated Receptora regulates a male-specific cytochrome P450 in mouse liver" Archives of Biochemistry and Biophysics 429: 231-236 article pdf

2003

  • Jackson, L., Bennett, A.J., Hawkey, C.J., Wahli, W., Michalik, L., Watson,S., Morrison, T., Anderton, K., Bell, D.R. and Smith, J. (2003) "Potential Role For PPARa in preventing colon cancer" Gut 52: 1317-1322 article pdf

  • Russell, A.P., Feilchenfeldt,J., Schreiber, S., Praz, M., Crettenand, A., Gobelet, C., Meier, C.A., Bell, D.R., Kralli, A., Giacobino, J.-P., and Deriaz, O. (2003) “Endurance Training in Humans Leads to Fiber Type–Specific Increases in Levels of Peroxisome Proliferator–Activated Receptor- Coactivator-1 and Peroxisome Proliferator–Activated Receptor- in Skeletal Muscle” Diabetes 52: 2874-2882 article pdf

2002

  • Combes, R., Balls, M., Bansil, L., Barratt, M., Bell, D., Botham, P., Broadhead, C., Clothier, R., George, E., Fentem, J., Jackson, M., Indans, I., Loizou, G., Navaratnam, V., Pentreath, V., Phillips, B., Stemplewski, H. and Stewart, J. (2002) “An Assessment of Progress in the Use of Alternatives in Toxicity Testing since the Publication of the Report of the Second FRAME Toxicity Committee” ATLA 30: 365-406

2000

  • Bell, D.R. and Poland., A. (2000) "Binding of AhR to AhR-Interacting Protein: the role of hsp90" Journal of Biological Chemistry 275: 36407-36414 PDF

  • Leclerq, I.A., Farrell, G.C., Field, J., Gonzalez, F.J., Bell, D.R. and Robertson, G.R. (2000) "Role of Cyp2e1 and Cyp4a enzymes as a microsomal catalysts of lipid peroxides in murine non-alcoholic steatohepatitis" J Clinical Investigation 105: 1067-75 PDF

  • Choudhury, A.I., Chahal, S., Bell, A.R., Roberts, R.A., Salter, A.M., Tomlinson, S.R. and Bell, D.R. (2000) "Species differences in peroxisome proliferation" Mutation Research 448: 201-212 PDF

1998

  • N.J. Plant, Horley, N.J., Dickins, M., Hasmall, S., Elcombe, C.R. and Bell, D.R. (1998) "The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate" Carcinogenesis19: 1521-1527 Abstract PDF

  • N.J. Plant, N.J. Horley, R.L. Savory, C.R. Elcombe, T.J.B. Gray and D.R. Bell (1998) "The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: glucocorticoid-induced PPARalpha is linked to peroxisome proliferator mitogenesis" Carcinogenesis19: 925-934 Abstract PDF

  • A.R. Bell, R. Savory, N.J. Horley, A.I. Choudhury, M. Dickins, T.J.B. Gray, A.M. Salter and D.R. Bell (1998) "Molecular basis of non-responsiveness to peroxisome proliferators: the guinea pig PPARalpha is functional and mediates peroxisome proliferator-induced hypolipidaemia" Biochemical Journal 332: 689-693 Abstract PDF

1997

  • Yee Heng's PhD Thesis

  • Y.M. Heng, C.-W. S. Kuo, P. S. Jones, R. Savory, R. M. Schulz, S. R. Tomlinson, T. J. B. Gray and D. R. Bell (1997) "A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and human" Biochemical Journal. 325: 741-749 PDF article Abstract

1996

  • I. E. Dulubova, V. G. Krasnoperov, M. V. Khvotchev, K. A. Pluzhnikov, T. M. Volkova, E. V. Grishin, H. Vais, D. R. Bell and P. N. R. Usherwood (1996) "Cloning and Structure of delta -Latroinsectotoxin, a Novel Insect-Specific Member of the Latrotoxin Family: Functional Expression Requires C-terminal Truncation" J. Biol. Chem. 271: 7535-7543 PDF article Abstract

  • Ashley, C.M., Simpson, M.G., Holdich, D.M and Bell, D.R. (1996) "2,3,7,8 tetrachlorodibenzo-p-dioxin is a potent toxin and induces cytochrome P450 in the crayfish, Pacifastacus leniusculus" Aquatic Toxicology, 35: 157-169 Abstract pdf article

1995

  • Jones, P.S., Savory, R., Barratt, P., Bell, A.R., Gray, T.J.B., Jenkins, N.A., Gilbert, D.J., Copeland, N.G. and Bell, David R. (1995) "Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine PPAR genes" Eur. J. Biochem. 233: 219-226 Abstract pdf article

  • Bell, D.R. (1995) "Dangerous Liaisons" Human and Experimental Toxicology 14: 536-537

  • Bell, D.R. (1995) "An overview of the symposium on Peroxisomes: biology and role in toxicology and disease', Aspen, Colorado, USA, June 28-July 2 1995" Human and Experimental Toxicology 14: 846-849

  • Bell, D.R. (1995) "A knockout for risk assessment" Human and Experimental Toxicology 14: 850-851

1994

  • Bell, D.R. (1994) "Epigenetic puzzle" Human and Experimental Toxicology 13: 907-908

1993

  • Bars, R.G., Bell, D.R. and Elcombe, C.R. (1993) "Induction of P450 4A and peroxisomal enzymes by clofibric acid in vivo and in vitro" Biochem. Pharmacol. 45: 2045-2053 pdf article

  • Bell, D.R., Plant, N.J., Rider, C.G., Na, L., Brown, S., Ateitalla, I., Acharya, S.K., Davies, M.H., Elias, E., Jenkins, N.A., Gilbert, D.J., Copeland, N.G. and Elcombe, C.R. (1993) "Species specific induction of cytochrome P450 4A: cloning of partial cDNAs from guinea pig, human and mouse"
    Biochem. J. 294: 173-180 pdf article

  • Bell, D.R. and Elcombe, C.R. "Peroxisome proliferation- lipid metabolism and receptors" (1993) in "Peroxisomes: Biology and Importance in Toxicology and Medicine", Eds G.G. Gibson and B.G. Lake. pp.137-149, Taylor and Francis Press, London.

  • Brackley, P.T.H., Bell, D.R., Choi, S.K., Nakanishi, K., Usherwood, P.N.R. (1993) "Selective antagonism of native and cloned kainate and NMDA receptors in xenopus oocytes" J. Pharmacol. Exp. Therapeut. 266: 1573-1580

1992

  • Bars, R.G., Bell, D.R., Elcombe, C.R., Oinonen, T., Jalava, T., Lindros, K.L. (1992) "Zone-specific inducibility of cytochrome P450 2B1/2 is retained in isolated perivenous hepatocytes" Biochem. J. 282: 635-638 pdf article

  • Bell, D.R., Bars, R.G. and Elcombe, C.R. (1992) "Differential tissue-specific expression and induction of cytochrome P450 4A1 and acyl-CoA oxidase " Eur. J. Biochem. 206: 979-986 pdf article

1991

  • Bell, D.R., Bars, R.G., Gibson, G.G. and Elcombe, C.R. (1991) "Localisation and differential induction of cytochrome P450IVA1 and acyl-CoA oxidase in rat liver" Biochem. J. 275: 247-252 pdf article

  • Bell, D.R. and Elcombe, C.R. (1991) "Induction of acyl-CoA oxidase and cytochrome P450IVA1 in primary cultures of rat hepatocytes" Biochem. J. 280: 249-253 pdf article

  • Bell, D.R. and Elcombe, C.R. (1991) "Regulation of differential splicing of acyl-CoA oxidase in the rat" Biochem. Biophys. Acta 1090: 211-215 pdf article

Updated on: 18/01/09
Apache web server
Contact: David R. Bell